In the ongoing battle against cancer, one formidable weapon is the Human Papillomavirus (HPV) vaccine. It's a crucial defence that's recommended not only for preteens but also for teens, young adults, and even some adults. With various types of HPV vaccines available, understanding who should get vaccinated, when, and the potential benefits are key in the fight against HPV-related cancers.
Who Should Get HPV Vaccine?
The Centers for Disease Control and Prevention (CDC) recommends HPV vaccination for preteens aged 11-12, with the option to start as early as age 9. This vaccination is vital for protecting against HPV infections that can lead to cancer later in life. Teens and young adults up to age 26 who missed the initial vaccination series should also get vaccinated. The CDC advises that 11- to 12-year-olds receive two doses of the vaccine, given 6 to 12 months apart. If the first dose is administered before the 15th birthday, only two doses are needed.

For those starting the series later, at ages 15 through 26, three doses are required. Children aged 9 through 14 who receive two doses less than 5 months apart will need a third dose. Individuals aged 9 through 26 with weakened immune systems are also recommended to receive three doses. However, vaccination is not recommended for everyone older than 26.
Adults aged 27 through 45 may choose to get the HPV vaccine after consulting with their doctor about their risk for new HPV infections and potential benefits. While the efficacy decreases in this age range due to prior exposure to HPV, some may still find value in getting vaccinated.
Who Should Not Get HPV Vaccine?
Before getting the HPV vaccine, individuals should inform their doctors about any severe allergies. Some people should avoid the vaccine if they have had a life-threatening allergic reaction to any ingredient or a previous dose of the HPV vaccine. Additionally, those allergic to yeast should not receive Gardasil and Gardasil 9. Pregnant individuals should also refrain from getting the vaccine.
The vaccine is generally safe for children who are mildly ill, but those with moderate or severe illnesses should wait until they recover.
Types of HPV Vaccines Are There
Three HPV vaccines-Gardasil 9 (9vHPV), Gardasil (4vHPV), and Cervarix (2vHPV)-have been licensed by the US Food and Drug Administration (FDA). Since late 2016, only Gardasil 9 has been distributed in the United States, protecting against nine HPV types.
All three vaccines guard against HPV types 16 and 18, which are responsible for most HPV-related cancers. The vaccines have demonstrated efficacy, with the potential to prevent more than 90% of HPV-attributable cancers.
Effectiveness Of These Vaccines Work
The effectiveness of HPV vaccines has been significant since their recommendation in 2006. Infections with HPV types causing most HPV cancers and genital warts have decreased by 88% among teen girls and 81% among young adult women. Fewer cases of genital warts and precancers of the cervix in young women have been reported.
The protection provided by the vaccines is long-lasting, with individuals followed for at least 12 years showing no evidence of decreasing immunity over time.
Possible Side Effects
While vaccines can have side effects, the majority of people who receive the HPV vaccine experience little to no adverse reactions. Mild side effects may include pain, redness, or swelling at the injection site, fever, dizziness, headache, fatigue, nausea, or muscle/joint pain. Fainting is more common among adolescents but can be prevented by having them seated or lying down during and after vaccination.
Severe allergic reactions are extremely rare, and those with severe allergies to any vaccine component should avoid vaccination.
Where Can I Find These Vaccines?
Access to HPV vaccines is widespread, available at doctor offices, community health clinics, school-based health centres, and health departments. If your doctor does not have the vaccine in stock, asking for a referral is recommended. State health departments can also provide information about where to get the HPV vaccine in your community.
How Do I Pay for These Vaccines?
Most health insurance plans cover routine vaccinations. The Vaccines for Children (VFC) program extends support to children 18 years and younger who are uninsured, underinsured, Medicaid-eligible, American Indian, or Alaska Native.
In the ongoing effort to eradicate HPV-related cancers, vaccination is a critical strategy. Understanding who should get the vaccine, the available types, their efficacy, and where to find them ensures that individuals of all ages can take proactive steps towards protecting their health. With the potential to prevent over 90% of HPV-attributable cancers, the HPV vaccine stands as a powerful ally in the fight against this prevalent and preventable threat.
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